After Macclesfield beat FA Cup holders Crystal Palace in the third round, BBC Sport looks at 10 of the biggest upsets in the competition's history.
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Four killed and five injured in head-on crash
Three teenagers and a man in his 50s died in the crash in Bolton, says Greater Manchester Police.
Trump tells Cuba to 'make a deal, before it is too late'
Trump has been turning his attention to Cuba since US forces seized Venezuelan leader Nicolás Maduro.
Iran warns it will retaliate if US attacks as protesters defy crackdown
Medics at two hospitals tell the BBC more than 100 bodies have been brought in over a two day period.
Leeds avoid upset with second-half comeback against Derby
James Justin scored his first goal for Leeds United since joining from Leicester City in the summer, in a second-half comeback after Derby County took the lead thanks to a Ben Brereton Diaz strike.
Trump won't take Greenland by force, Mandelson says
The former UK ambassador to the US tells the BBC the president's advisers would likely warn him against the move.
Tories would ban under-16s from social media
Kemi Badenoch has promised to follow the example of Australia, which became the first country to introduce the policy last month.
Cold snap set to ease ahead of wet and windy week
Milder conditions are expected after days of snow, ice and strong winds.
Mystery of wolf-type dogs solved with DNA test
Three "wolf-dogs" found roaming the streets of Preston were first thought to be German Shepherds.
Tories will channel anger at Labour, vows Badenoch
The Conservative leader says her party has started to offer more than "reflexive" opposition to the government.
Bride and groom killed by gas explosion day after Pakistan wedding
Eight people were killed after a gas cylinder exploded at a house the morning after the wedding celebration.
Liverpool's Bradley out for season with knee injury
Liverpool defender Conor Bradley is ruled out for the rest of the domestic season after suffering a significant knee injury, involving damage to bone and ligament.
'What a catch!' - Rams avoid play-off upset with 38 seconds remaining
Colby Parkinson scores a touchdown with 38 seconds remaining as the Los Angeles Rams leave it late to beat the Carolina Panthers 34-31 to avoid a play-off upset.
Potholes map rates council road repair progress
Thirteen local authorities received a "red rating" on the Department for Transport mapping tool for England.
Epstein kept me 'separate' from his sexual side because I'm gay, Mandelson tells BBC
In his first interview since being sacked as the UK's US ambassador, Lord Mandelson says he never saw any young women at Epstein's properties.
Lorraine Kelly pays tribute to father after 'shock' death
Lorraine Kelly has paid tribute to her 84-year-old father after his death in East Kilbride in Scotland.
Sabalenka beats Kostyuk to win third Brisbane title
World number one Aryna Sabalenka prepares for the Australian Open with a 6-4 6-3 victory over Marta Kostyuk to win a third Brisbane International title.
Winners and Sinners: What to expect from the Golden Globes
Marty Supreme, Sinners and One Battle After Another are the films competing at this year's ceremony.
Winners and Sinners: What to expect from the Golden Globes
Marty Supreme, Sinners and One Battle After Another are the films competing at this year's ceremony.
Thousands march and dozens arrested in Minneapolis protests against ICE
Days after the death of Renee Good, protests continue in Minneapolis and cities across the US.
Thousands march and dozens arrested in Minneapolis protests against ICE
Days after the death of Renee Good, protests continue in Minneapolis and cities across the US.